Systematic review of radical hysterectomy in women with cervical cancer

Authors

DOI:

https://doi.org/10.5281/zenodo.14892644

Keywords:

hysterectomy, gynecological neoplasia, surgical treatment

Abstract

Cervical cancer remains a major challenge and a global health concern, affecting thousands of women worldwide. In the early stages of the disease, radical surgery, specifically hysterectomy, is considered the most appropriate and recommended treatment. This procedure seeks to offer a quick and effective solution, given the high mortality rate associated with this type of cancer. In order to delve deeper into this topic, the present study proposed to carry out a systematic review following the PRISMA protocol. Studies published between 2018 and 2025 were analyzed, located in databases such as Scopus, Scielo, Medline, Pubmed and Latindex; Of the total of 150 related works, a total of 22 articles were exhaustively delved into, in which studies that compile and present relevant information about the treatment in question were identified. From the analysis, it is concluded that radical hysterectomy remains the treatment of choice for women with cervical cancer, consolidating itself as the gold standard to prevent future complications.

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References

Álvarez, C., Castro Nessim, E., Martín Virginillo, J., Bruno, G., González, C., Vallejos, J., & Dieguez, A. (2012). Actualización de la estadificación de cáncer de cuello uterino. Revista argentina de radiología, 76(2). https://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1852-99922012000200013

Ben, S., Greif, D., Nozar, Ma. F., Calderon, J., & Fernandez, M. X. (2018). Tratamiento radical mínimamente invasivo en cáncer de cuello uterino invasor: experiencia de la Clínica Ginecotocológica A. Revista Médica del Uruguay, 34(2). https://doi.org/10.29193/rmu.34.2.2

Brandt, B., Levin, G., & Leitao, M. M. (2022). Radical hysterectomy for cervical cancer: the right surgical approach. Current Treatment Options in Oncology, 23(1), 1–14. https://doi.org/10.1007/s11864-021-00919-z

Darin, C., Guilmi, J. Di, Verdura, R., Sardi, J., & Maya, G. A. (2016). Histerectomía radical laparoscópica: ¿un nuevo estándar en el tratamiento del cáncer de cuello uterino? Fronteras en Medicina, 11(1), 13–16. http://adm.meducatium.com.ar/contenido/articulos/4800130016_311/pdf/4800130016.pdf

Dos Santos Galindo, M. V., & Salazar Plaza, J. A. (2022). Histerectomía radical en el tratamiento del cáncer de cuello uterino. Factores pronósticos. http://hdl.handle.net/10872/22277

Hillemanns, P., Hertel, H., & Klapdor, R. (2020). Radical hysterectomy for early cervical cancer: what shall we do after the LACC trial? Archives of Gynecology and Obstetrics, 302(2), 289–292. https://doi.org/10.1007/s00404-020-05627-x

Kazmierczak, K., & Nowakowski, B. (2021). Radical hysterectomy and its importance in the concept of cervical cancer treatment. Ginekologia Polska, 92(2), 1–4. https://doi.org/10.5603/GP.a2020.0148

Kehoe, S. (2020). Radical hysterectomy for cervical cancer: reducing ureteric injuries. BJOG: An International Journal of Obstetrics & Gynaecology, 127(7), 866. https://doi.org/10.1111/1471-0528.16181

Kim, H. S., Kim, R., & Lee, M. (2017). Super-radical hysterectomy for recurrent cervical cancer. Surgical Oncology, 26(4), 331–332. https://doi.org/10.1016/j.suronc.2017.07.003

Lovell, D. Y., & Naumann, R. W. (2022). The benefits of laparoscopic radical hysterectomy for cervical cancer: res ipsa loquitur? Journal of Minimally Invasive Gynecology, 29(7), 805–806. https://doi.org/10.1016/j.jmig.2022.05.011

Matsuo, K., Matsuzaki, S., Mandelbaum, R. S., Chang, E. J., Klar, M., Matsushima, K., Grubbs, B. H., Roman, L. D., & Wright, J. D. (2020). Minimally invasive radical hysterectomy for early-stage cervical cancer: Volume-outcome relationship in the early experience period. Gynecologic Oncology, 158(2), 390–396. https://doi.org/10.1016/j.ygyno.2020.05.009

Melamed, A., Rauh-Hain, A., & Ramirez, P. (2019). Minimally invasive radical hysterectomy for cervical cancer: when adoption of a novel treatment precedes prospective, randomized evidence. Journal of Clinical Oncology, 37(33). https://doi.org/10.1200/JCO.19.01164

Mora, E., Gallego, P. A., & Fuentes, J. S. (2018). Histerectomía radical por cáncer de cuello uterino. Repertorio de Medicina y Cirugía, 27(1). https://doi.org/10.31260/RepertMedCir.v27

Nakasone, T., Taira, Y., Shimoji, Y., Arakaki, Y., Nakamoto, T., Ooyama, T., Kudaka, W., Kaneshima, I., Nishihira, K., Mekaru, K., & Aoki, Y. (2020). Hysterectomy for recurrent/residual cervical cancer following definitive radiotherapy. In Vivo, 34(4), 2173–2177. https://doi.org/10.21873/invivo.12026

Pérez Villena, J. F. (2024). Current treatment of cervical cancer: progress and prospects. Revista Peruana de Ginecologia y Obstetricia, 70(4). https://doi.org/10.31403/rpgo.v70i2695

Plante, M., Kwon, J. S., Ferguson, S., Samouëlian, V., Ferron, G., Maulard, A., de Kroon, C., Van Driel, W., Tidy, J., Williamson, K., Mahner, S., Kommoss, S., Goffin, F., Tamussino, K., Eyjólfsdóttir, B., Kim, J.-W., Gleeson, N., Brotto, L., Tu, D., & Shepherd, L. E. (2024). Simple versus radical hysterectomy in women with low-risk cervical cancer. New England Journal of Medicine, 390(9), 819–829. https://doi.org/10.1056/nejmoa2308900

Poddar, P., & Maheshwari, A. (2021). Surgery for cervical cancer: Consensus & controversies. Indian Journal of Medical Research, 154(2), 284–292. https://doi.org/10.4103/ijmr.IJMR_4240_20

Raspagliesi, F., & Bogani, G. (2019). Radical surgery for cervical cancer. The Lancet Oncology, 20(9), 1198–1199. https://doi.org/10.1016/S1470-2045(19)30409-7

Sakuragi, N., Murakami, G., Konno, Y., Kaneuchi, M., & Watari, H. (2020). Nerve-sparing radical hysterectomy in the precision surgery for cervical cancer. Journal of Gynecologic Oncology, 31(3). https://doi.org/10.3802/jgo.2020.31.e49

Smith, A. J. B., Jones, T. N., Miao, D., & Fader, A. N. (2021). Minimally invasive radical hysterectomy for cervical cancer: a systematic review and meta-analysis. Journal of Minimally Invasive Gynecology, 28(3), 544-555.e7. https://doi.org/10.1016/j.jmig.2020.12.023

Suarez-Cadena, F. C. (2018). Terapéutica del cáncer de cuello uterino, una revisión de la literatura. MedUNAB, 21(1), 100–114. https://doi.org/10.29375/01237047.2583

Published

2025-02-19

Issue

Section

Communication of Science: Bibliometrics and systematic reviews.

How to Cite

Systematic review of radical hysterectomy in women with cervical cancer. (2025). InveCom Journal, 5(4), 1-8. https://doi.org/10.5281/zenodo.14892644

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